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Anti-Obesity Effect of Garlic-added Kochujang in 3T3-L1 Adipocytes
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  • Anti-Obesity Effect of Garlic-added Kochujang in 3T3-L1 Adipocytes
  • Anti-Obesity Effect of Garlic-added Kochujang in 3T3-L1 Adipocytes
저자명
Kong. Chang-Suk,Park. Kun-Young
간행물명
Journal of food science and nutrition
권/호정보
2008년|13권 2호|pp.66-70 (5 pages)
발행정보
한국식품영양과학회
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정기간행물|ENG|
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
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기타언어초록

In order to develop a functionally improved kochujang with antiobesity effects, garlic-added kochujang was prepared with freeze-dried garlic powder and followed by fermentation for 60 days at $30^{circ}C$. Antiobesity effect of the garlic-added kochujang was investigated by measuring the leptin secretions and mRNA expression levels of obesity-related gene such as TNF${alpha}$, PPAR${gamma}$, C/EBP${alpha}$, and SREBP1c, in cultured 3T3-L1 adipocytes. Fermentation of garlic-added kochujang led to decreased levels of leptin secretions and reduced the mRNA expression levels of TNF${alpha}$, PPAR${gamma}$, C/EBP${alpha}$, and SREBP1c in the 3T3-L1 adipocytes. Accordingly, these results suggest that the addition of garlic to kochujang has a potential as a valuable functional food for controlling obesity.