Every field of studies form its theory through its universal method and own method based on respective views with its own culture and contributes to academic advancement with appropriate research methodology within theory. Therefore, If methology of oriental medicine is not include universal method and particularity method in research methology, it will not obtain scientific character and lose its logic. The methology of oriental medicine is classified by two approaches, universal methology of natural science which inspect the effect through experimentation on the fact, and particularity methology of human science which understand the effect through translation on the value(politics, economics, society, philosophy, history and culture). In this paper, the methodology of oriental medicine contains duality including both universality and particularity.