This paper proposes a new neuron control strategy for an active vehicle suspension system, with the emphasis on the study of multivariable and uncertain suspension characteristics. The novelty of this strategy is in the use of integrated error, which consists of multiple output errors in the regulated plant. By combining the integrated error approach with the traditional neuron control (TNC), integrated error neuron control (IENC) is presented. It provides a direct control to the multiple outputs of the control plant simultaneously. Taking a quarter-car model as an example, the proposed control strategy is applied and comparative simulations are carried out with various vehicle parameters and road input conditions. Simulation results prove the effectiveness and robustness of the proposed IENC method. In addition, the newly proposed neuron scheme provides a simple yet efficient new possibility for the control of a class of uncertain multivariable systems similar to an active vehicle suspension.