For teaching-learning to geological region of earth science part in science education, middle school, the practical uses of natural science museum are very effective. So, the appropriate uses of the natural science museum are necessary for the teaching and learning of Science Education. This study aims to consider the presentation characteristics of the natural science museum and to examine how is effective it to geological region in middle school science curricula on those uses. From the results, the natural science museum is low in multi-sided and open-endedness presentation characteristics but high in ones of accessible characteristic. And its presentations are good in multimodal characteristics using supported materials but relatively low in relevant and multimedia ones. In the museum, diorama and self-performing presentation types are not but internet ones are most. The presentations of the natural science museum are mainly assigned to knowledge region linked to basic science concepts but relatively insufficient in STS aspects, on the basis of connection the presentations with middle school science curricula. It is respected that these insufficiencies might be diminished by variable arrangements of and explanations to the presentations for understanding improvements. And, applies to the presentations in STS may be encountered, if multi-sided observations to them is available.