Purpose: This study is to develop a hypothetical structural model of the quality of life of single aged women and to explain the compatibilities between the models and actual data. Methods: Ten theoretical variables were used to evaluate of the quality of life of single aged women. 300 of single aged women were selected as the subjects. A hypothetical prediction model of quality of life was tested by the covariance structure analysis with PC-LISREL 8.12. Results: Economy, religion activity, leisure activity, social support, self-esteem, depression and health prompting behavior were the significant variables which affected to the quality of life directly in the single aged women. But social support, self-esteem affected to them indirectly. Knowing perceived health status directly but it affected indirectly to the quality of life in single aged women. Conclusion: In this study, it was discovered that self-esteem was the most important factor to affect to the quality of life in single aged women and the next was the depression and health promoting behavior. As a result, it was discovered that age, economic status, self-esteem and depression were the significant factors to affect to the quality of life in single aged women.