The structural characteristics that influence on the fungicidal activities of N-phenylbenzenesulfonamide (1~24) and N-phenyltheinylsulfonamide (25~30) derivatives against Dampping-off (Pythium ultimum) were discussed quantitatively using the models of molecular holographic quantitative structure-activity relationships (HQSAR). From the based on these findings, the statistical results of the optimized HQSAR F-3 model showed better predictablity ($r^2_{cv.}$ or $q^2=0.581$) and correlation coefficient ($r^2_{ncv.}=0.963$). And, from the analytical results of the atomic contribution maps on the fungicidal activities, the most active compound is $R_1=2-fluoro-4-chloro$ substituent (4) and the most inactive one is $R_1=4-methoxy$ substituent (20). It was found that the 2-fluoro-4-chlorophenyl group as a $R_1$-group was an important structure and a characteristic factor not only for herbicidal activity but also for fungicidal activity.