The present work aims to determine the overall pressure losses in the shell from the point of entry of the fluid to the outlet point of fluid of shell and tube heat exchanger. The main contribution of the present work is concerned with calculating the pressure drop in the interior section and window section. Shell-side flow velocity distributions have been evaluated. We assume that the shell-side fluid is turbulent. The calculation procedure is based upon the Delaware method. Evaluation of pressure drop on the shell side will be helpful for a designer or manufacturer of a heat exchanger.