Purpose: The purpose of this study was to evaluate the effects of hydroxyapatite containing toothpaste for patients who received periodontal therapy and felt hypersensiptivity. Material and Methods: After application of toothpaste, patients were evaluated for VAS(Visual Analog scale) scores to a cold stimulate on baseline, 1 week, and 4 weeks. VAS scores were analyzed by statistical methods. Results: The results of this study were as follows. 1. VAS scores in control group on baseline, 1 week, 4 weeks were $5.39{pm}2.05$, $4.75{pm}2.00$, $4.21{pm}1.75$. 2. VAS scores in experimental group on baseline, 1 week, 4 weeks were $5.61{pm}2.37$, $4.81{pm}2.46$, $4.08{pm}2.54$. 3. Decrease of VAS scores on hypersensitivity after 1week was $0.64{pm}0.49$(p<.0001) in control group, $0.80{pm}1.65$ (p<.0001) in experimental group. 4. Decrease of VAS scores on hypersensitivity after 4weeks was $1.18{pm}1.60$(p<.0001) in control group, $1.53{pm}1.88$ (p<.0001) in experimental group. 5. When compared, decrease of VAS scores after 1 week between 2 groups were not statistically different(p=0.2622). 6. When compared, decrease of VAS scores after 4 weeks between 2 groups were not statistically different(p=0.1219). Conclusion: It was confirmed that hydroxyapatite containing toothpaste have the similar effect with pre-existing proven dentifrice for relieving teeth hypersensitivity.