An experimental study of the flame response in a turbulent premixed combustor has been conducted with room temperature, atmospheric pressure inlet conditions using premixed natural gas. The fuel is premixed with the air upstream of a choked inlet to avoid equivalence ratio fluctuations. Therefore the observed flame response is only the result of the imposed velocity fluctuations, which are produced using a variable speed siren. Measurements are made of the velocity fluctuation in the nozzle using hot wire anemometry and of the heat release fluctuation in the combustor using chemiluminescence emission. The results are analyzed to determine the phase and gain of the flame transfer function as a function of the modulation frequency. Of particular interest is the effect of flame structure on the flame response predictions and measurements. The results show that both the gain and the phase of flame transfer function are closely associated with the flame length and structure, which is dependent upon the upstream flow perturbation as well as equivalence ratio in the current study.