In this paper, we proposed to improve performance of the design of a cascade controller with the smith-predictor structure. The parameters of controller in the inner loop are determined to minimize the integral of time multiplied by the absolute value of error (ITAE) value of performance Index. The controller of outer loop and parameters of Smith-Predictor can be obtain using reduction model. The model reduction is considered that it is the transient response and the steady-state response through the use of nyquist curve. Simulation examples are given to show the better performance of the proposed method than conventional methods.