Purpose: This study was done to identify the risk factors influencing turnover intention of nurses. Method: The participants in this descriptive survey on causal relations were 756 nurses who were working at a tertiary university hospital in Seoul. The data were put in to multiple regression analysis to build a prediction model. Results: Turnover intention according to general features were shown as following.: Age, Clinical careers, Educational level, Marital status, Economic status(Yearly income). The relationship between turnover intention and job stress had positive correlation. But the relationship between turnover and other factors that job satisfaction, internal marketing, and organizational commitment had negative correlation. The causal factors of turnover intention were organizational commitment, the factors of organizational support and patient/caregiver relationships among subcategories of job stress and the factor of professional position among subcategories of job satisfaction. Conclusions: The findings of study suggest that board intervention program should be provided to prevent problems of turnover. It is also recommended that a program be developed that can help control the variables identified in this study along with follow up study to verify the model.