Although the relationship between physical health problems and life satisfaction is well documented, less is known about the role of coping strategies, in particular strategies for coping via religious or spiritual means. To investigate the relationships among these factors, data collected with questionnaires completed by 326 adult alcoholics at a rehabilitation agency. Significant Physical Health Problem $ imes$ Religious Coping buffer interactions were found in the relationship between physical health problem and life satisfaction. Moderated regression analysis showed that religious coping reduced the impact of physical health problem on life satisfaction. Implications for practice are discussed.