Consider a multi-floor facility with multiple rooms of unequal size on each floor. Students come from many organizations to attend the conference to be held at this facility. In assigning the rooms to the students, several constraints must be met; such as boys and girls must not be assigned to the rooms on the same floor. Given the capacity of each room and the number of students from each organization, the problem is assigning students to rooms under a set of constraints and various objectives. We present six models with different objective functions; and formulate them as binary integer programming problems. A numerical example and a case study follow to illustrate the proposed models.