Purpose: The purpose of this study was to investigate parenting attitudes and to identify factors influencing this parenting attitude in mothers of children with hemophilia. Method: The participants in this study were 119 mothers of children with hemophilia (under 18 years of age) who were registered members of the Korea Hemophilia Foundation. Data were collected using the Mother-Infant Attachment Scale, Maternal Guilt Scale and Parenting Attitude Scale. The collected data were analyzed using SPSS program. Results: The parenting attitude was 3.02 (total possible score=4). By subcategories, achievement attitude was the highest (3.45). Of the factors influencing parenting attitudes, mother-child attachment, maternal guilt and self-esteem account for 45.6% of the variance. Conclusion: The findings of this study show that attitudes of parents of children with hemophilia were positive. As mother-child attachment and maternal guilt were identified as major factors in predicting parenting attitudes, there is a need to consider interventions that will increase mother-child attachment and decrease maternal guilt.