기관회원 [로그인]
소속기관에서 받은 아이디, 비밀번호를 입력해 주세요.
개인회원 [로그인]

비회원 구매시 입력하신 핸드폰번호를 입력해 주세요.
본인 인증 후 구매내역을 확인하실 수 있습니다.

회원가입
서지반출
Comparison of the Permeability of Stilbene Analogues in Caco-2 Cells
[STEP1]서지반출 형식 선택
파일형식
@
서지도구
SNS
기타
[STEP2]서지반출 정보 선택
  • 제목
  • URL
돌아가기
확인
취소
  • Comparison of the Permeability of Stilbene Analogues in Caco-2 Cells
  • Comparison of the Permeability of Stilbene Analogues in Caco-2 Cells
저자명
Kim. Su-Na,Ahn. Ji-Yun,Shon. Dong-Wha,Kim. Ji-Sun,Kim. Mi-Hye,Ha. Tye-Youl
간행물명
Food science and biotechnology
권/호정보
2008년|17권 3호|pp.675-678 (4 pages)
발행정보
한국식품과학회
파일정보
정기간행물|ENG|
PDF텍스트
주제분야
기타
이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
서지반출

기타언어초록

Permeability of resveratrol, piceid, rhapontigenin, and rhaponticin in Caco-2 cell assays using high-performance liquid chromatography were compared. Caco-2 cell monolayers were used to evaluate the transport rates of stilbene analogues from the apical to the basolateral sides. All stilbenes experimented in this study were transported to the basolateral side by times. For comparing the permeability of 4 stilbenes, we calculated the slope of the cumulative concentration of each stilbene in basolateral sides over time, resulting in those values of resveratrol, piceid, rhapontigenin, and rhaponticin with $3.766{ imes}10^{-5}$, $4.330{ imes}10^{-6}$, $5.430{ imes}10^{-5}$, and $2.458{ imes}10^{-5};{mu}M/sec$, respectively. Apparent permeability coefficient of resveratrol and rhapontigenin were calculated to $9.994{ imes}10^{-6}$ and $1.441{ imes}10^{-6};cm/sec$, respectively, while those of piceid and rhaponticin were to $1.149{ imes}10^{-7}$ and $6.523{ imes}10^{-7};cm/sec$, respectively. These results suggest that aglycones would be absorbed more effectively than glycosides in stilbenoids.