Recently a lot of researches have been conducted on the progressive collapse of structures which is the total collapse of structures initiated by localized damage. Most of the previous studies on the field of progressive collapse have followed deterministic approach without considering uncertainty involved in design variables, which results in unknown reliability of the analysis results. In this study the sensitivity analyses are carried out with design variables such as yield strength, live load, damping ratio, and elastic modulus on the vertical deflection of the joint from which a column is suddenly removed. The Monte Calro simulation, tornado diagram method, and the first order second moment method(FOSM) are applied for the sensitivity study. According to the nonlinear static analysis results, the vertical deflection is most affected by the variation of yield strength of beams. The nonlinear dynamic analyses show that the behaviour of model structures is highly sensitive to variation of the yield strength of beams and the structural damping ratio.