Structural analysis models to develop live load distribution factors of simply supported prestressed concrete I-girder bridge should have the precision of the analysis results as well as modeling simplicity. This is due to the numerous frequency of structural analysis needed while developing live load distribution factors. In this study, an appropriate structural analysis model is selected by comparing previous researchs studies and models used in practical design. Also, the influence by the flexural stiffness of barrier and diaphragm on the live load distribution had been analyzed through comparing the numerical analysis and experimental tests. As a result, the model that the eccentric girder and the barrier and diaphragm are connected to the deck plate was appropriate in satisfying both accuracy and simplicity for structural analysis of simply supported prestressed concrete I-girder bridge. However, the barrier was analyzed to have insignificant influence on the live load distribution in spite of its variation of stiffness. The eccentric diaphragm showed little influence at 25% or higher of flexural stiffness. From the results, a model that the girder is rigidly connected to the deck plate in consideration of the eccentricity, the barrier is ignored and the whole section of diaphragm is supposed to be valid without eccentricity is decided as the most appropriate structural model to develop the live load distribution factors of simply supported prestressed concrete I-girder bridge in this study.