The 21st century is often called the knowledge-based information society. A new term, Data Technology (DT), which handles data and creation of information, is defined. A few important concepts of DT which are related to Six Sigma are described. Also some characteristics of Knowledge Management (KM) which provide new knowledge are explained. As a new direction of Six Sigma, Six Sigma Focused on Knowledge Creation (SSFKC) is suggested. The way of implementation of SSFKC and its relationship with DT and KM are elaborated.