The optimal operation in distribution system is to select tie switches considering important elements(Load balance, Loss minimization, Voltage drop, Restoration index..) in distribution system. Optimal Tie Switches Selection is very important in operation of distribution system because that is closely related with efficiency and reliability. In this paper, a new algorithm considering important elements is proposed to find optimal location of tie switches. In the case study, the proposed algorithm has been testified using real distribution network of KEPCO for verifying algorithm and complex network for applying future distribution network.