The slip velocity and the temperature jumps for low-speed flow in microchannels are investigated using Langmuir slip boundary condition. This slip boundary condition is suggested to simulate micro flow. The current study analyzes Langmuir slip boundary condition theoretically and it analyzed numerically micro-Couette flow, micro-Poiseuille flow and grooved microchannel flow. First, to prove validity for Langmuir slip condition, an analytical solution for micro-Couette flow is derived from Navier-Stokes equations with Langmuir slip conditions and is compared with DSMC and an analytical solution with Maxwell slip boundary condition. Second, the numerical analysis is performed for micro-Poiseuille flow and grooved microchannel flow. The slip velocity and temperature distribution are compared with results of DSMC or Maxwell slip condition and those are shown in good agreement.