Tai Chi is a slow and gentle exercise which is suitable for obese women with chronic diseases. Tai Chi can improve the health of a senior without exacerbating existing impairments, including obese patients. The purpose of this study was to evaluate the effects of different types of Tai Chi exercise on blood variables (glucose, cholesterol, TG, HDL, LDL, cortisol) and physical fitness (muscle strength, flexibility, muscle endurance, agility, balance). Thirty obese women were recruited from a public health center. They were divided into Yang style (YS: n=15) and 12 (12KS: n=15). The Tai Chi exercise group participated in a training program for 12 weeks (3times/week). There was significant improvement in muscle strength, flexibility, and muscle endurance in both groups. Agility was significantly increased in YS, more than in 12KS. However, there was no improvement in balance in both groups. There was significant improvement in cholesterol, HDL, LDL, and cortisol in both groups. However there was no improvement in blood glucose levels in either group. From the results, there was no significant difference in either Tai Chi exercises. The Tai Chi exercise program was effective in improving cholesterol related variables and physical fitness, except balance, in both groups. Further study is needed in this area.