In order to enhance the functionality of a cotton fabric actually used as a clothing material for patients, the fabrics were treated with a chitosan/nanosilver mixed solution. The nanosilver had excellent biocompatibility, provided expectation of an additional performance, did not harm human beings, and supplements chitosan, which was disadvantaged if used alone for fabric treatment. The nanosilver was mixed thereto and a treatment effect due to a mixing ratio was considered. This study was observed through mechanical properties and hand value which were the important function. The treatment of chitosan/nanosilver mixed solution gave a smoother surface than the treatment of chitosan alone. As a result of evaluation of the forms according to KES-FB system, Koshi was deduced, and both Numeri and Fukurami were increased. Thereby, the cotton fabric was a little smooth to provide elasticity, due to the treatment of chitosan/nanosilver mixed solution. THV of the treated fabrics calculated from this basis increased at all mixing ratio as compared with the untreated fabric. The fabrics treated with chitosan/nanosilver mixed solution were shown a better THV than the fabric treated with chitosan alone.