This paper presents an automatic LCD gamma control system using gamma curve optimization. It controls automatically gamma adjustment registers in mobile LCD driver IC to reduce gamma correction error and adjusting time. The proposed gamma system contains Module-Under-Test (MUT, LCD module), PC installed with program, multimedia display tester for measuring luminance, and control board for interface between PC and LCD module. Proposed algorithm and program are applicable for most of the LCD modules. It is realized to calibrate gamma values of 1.8, 2.0, 2.2 and 3.0. The control board is designed with DSP and FPGA, and it supports various interfaces such as RGB and CPU. Developed automatic gamma control system showed significantly reduced gamma adjusting time of 240 sec. and much less average gamma error of 11% than 42h and 27% with conventional manual method. We believe that the proposed system is very useful to provide high-quality LCD and to improve production process.