High speed railway challenge the design, construction and maintaining of traditional railway, many traditional design concepts have been changed. Transition of railway and bridge has two main problems. one is that different lines have different ability of resisting distortion in area of trial load, which was known that problem of smooth transition of stiffness, the other is that differential settlement between artificial structure and earth structure cause bending of railway. The two problems have effect on train moving. The principle of processing transition of railway and bridge is same in world, but it is difficult to find relationship between design standard of transition, vehicle performance, line standard, design speed and so on form documentation and data reports. Based on mechanics, the paper analyzed dynamic performance of transition of high speed railway, studied various rough elements which is effective to train moving, built mathematical model of interaction of train and transition of high speed railway and developed numerical simulation software. In various different work conditions, we did great quantity of numerical simulation, comprehensive analysis and performance analysis.