This study is to develop a human resource (HR) security framework, and related HR security indicators in the context of information security. The HR security framework consists of three constructs, personnel assurance, personnel competence, and personnel security control. Based on the framework, HR security management indicators are derived as 26 indicators in 9 items out of 3 categories. An empirical research has been performed to verify the relevance and consistency between the indicators by conducting a questionnaire-based survey. Also, interrelationships between the proposed indicators and HR related security level were analyzed by the multiple regression analysis. As a result, the proposed hypothesis were mostly accepted, showing the significant relationships between the indicators and security level.