Purpose: This study was conducted to evaluate the relationship between self-control behavior, social comparison attitude, self-efficacy and health promotion activities of college students who had health related majors (nursing, dental hygiene, health administration). Methods: The subjects consisted of 413 college students. Data were collected by self reported questionnaires that were designed to evaluate self-control behavior, social attitudes, self-efficacy and health promotion lifestyle (HPLP). Data were analyzed using the SPSS/PC win 14.0 program. Results: Upward & parallel comparison, self-efficacy and parents income were positively correlated with health promotion activities by college students. The most significant predictors of health promotion activities for college students were self-efficacy and self-control behavior. Conclusion: Health promotion activities for college students are influenced by self-efficacy, self-control behavior, and upward comparison. In conclusion, to increase the health promotion activities of college students, methods designed to increase self-efficacy should be prepared while considering the self-control behavior and comparative propensity towards others.