A mobile ultrasound scanner developed for use in point-of-care applications is introduced, which can not only provide ultrasound images but can also measure various bio-signals. The mobile ultrasound scanner is also designed to meet the demanding requirements for point-of-care diagnosis, such as battery-powered operation, portability in terms of size and weigh, and real-time wireless communications capability for remote diagnosis. To meet these requirements, an efficient beamforming method for high resolution imaging with a small number of active elements, a hardware efficient beamformer architecture, and echo processing algorithms with greatly reduced computational complexity have been developed. Experimental results show that the prototype mobile ultrasound scanner is fully functional and satisfies most of the design requirements.