A robust L1 data depth was used in clustering and classification, so called DDclus and DDclass by Jornsten (2004). SVM-based classification works well in most of the situation but show some weakness in the presence of outliers. Proper gene selection is important in classification since there are so many redundant genes. Either by selecting appropriate genes or by gene clustering combined with classification method enhance the overall performance of classification. The performance of depth based method are evaluated among several SVM-based classification methods.