The long-term behaviour of simply supported composite steel-concrete beams with deformable connectors subjected to skew bending and torsion is presented. The problem is dealt with by recurring to the displacement method, assuming the bending and torsional curvatures and the longitudinal deformations of each sectional part as unknowns and obtaining a system of differential and integro-differential equations. Some solving methods are presented, in order to obtain exact and approximate solutions and evaluate the precision of the approximate ones. A case study is then presented. For the sake of clearness, the responses of the composite beam under loads applied in different directions are studied separately, in order to correctly evaluate the effects of each load condition.