A fuzzy-sliding mode controller is presented to control the dynamics of semi-active suspension systems of vehicles using magneto-rheological (MR) fluid dampers. A full car model is used to design and evaluate the performance of the proposed semi-active controlled suspension system. Four mixed mode MR dampers are designed, manufactured, and integrated with four independent sliding mode controllers. The siding mode controller is designed to decrease the energy consumption and maintain robustness. In order to overcome the chattering of the sliding mode controllers, a fuzzy logic control strategy is merged into the sliding mode controller. The proposed fuzzy-sliding mode controller is designed and fabricated. The performance of the semi-active suspensions is evaluated in both the time and frequency domains. The obtained results demonstrate that the proposed fuzzy-sliding mode controller can effectively suppress the vibration of vehicles and improve their ride comfort and handling stability. Furthermore, it is shown that the "chattering" of the sliding mode controller is smoothed when it is integrated with a fuzzy logic control strategy. Although the cost function of the fuzzy-sliding mode control is a slightly higher than that of a classical LQR controller, the control effectiveness and robustness are enhanced considerably.