Short column effect is cause to failure of columns which may result in severe damages or even collapse during earthquakes. The scope of the study is mainly to reveal the effect of short column on the holistic behaviour of the buildings. The nonlinear analysis of 31 different frame buildings containing short column problem are carried out using finite element method. The finite element models were selected by 2 bays and 3 stories. Since the short columns are generally seen in the first storey of the buildings, in the study, they are only constructed in the same storey. The adverse effect of the short column on the response of buildings was shown in terms of the total load factor and displacement capacity of building. The response of buildings in terms of ground storey displacements is presented in figures and discussed. It is revealed that if the window openings are constructed along the bays, the total load capacity is decreased 85% compared with reference model in which all of bays are filled with infill walls.