The purpose of this study was to investigate the relationships among attachment with parents, self-differentiation, and stress coping strategies. The participants of the present study were 142 male and 161 female college students in Jeolla-Do province. The data were collected by self-administered questionnaire method. The major results of this research were as follows. First, there was significant positive correlation between the level of attachment with parents and self-differentiation, indicating that the greater the level of attachment with parents, the higher the level of self-differentiation. Second, active coping was associated with higher levels of differentiation of self and passive coping were associated with lower levels of differentiation. Third, there was significant positive correlation between the level of attachment with parents and active coping, indicating that the greater the level of attachment with parents, students used more active coping than passive coping. Finally, multiple regression analysis were performed to attachment with parents and self-differentiation. It was found that attachment with parents was the most powerful predictor of active coping and self-differentiation was the most powerful predictor of passive coping.