This research proposes an automatic torsion beam axle optimization process with a multidisciplinary approach and generates the optimal torsion design parameters, such as thickness and shape. In order to construct an automatic analysis process, multidisciplinary analysis models, such as modal analysis, roll mode dynamic analysis, and fatigue analysis, were applied in batch mode. To understand the design space, a parametric study using the torsion beam thickness and shape was performed. Considering roll durability and K&C characteristics, the torsion beam axle could be optimized. For the automated design process, a PIDO tool called PIAnO was used. In conclusion, a reduction in the computer-aided simulation time was achieved, and the durability and K&C characteristics of the torsion beam were enhanced by optimizing the thickness and shape.