In the past few decades, effects of natural hazards, such as earthquakes and wind, on existing structures have attracted the attention of researchers and designers. More recently, however, the phenomenon of progressive collapse is becoming more recognized in the field of structural engineering. In practice, the phenomenon can result from a number of abnormal loading events, such as bomb explosions, car bombs, accidental fires, accidental blast loadings, natural hazards, faulty design and construction practices, and premeditated terrorist acts. Progressive collapse can result not only in disproportionate structural failure, but also disproportionate loss of life and injuries. This paper provides an up-to-date comprehensive review of this phenomenon and its momentousness in structural engineering communities. The literature reveals that although the phenomenon of progressive collapse of buildings is receiving considerable attention in the professional engineering community, more research work is still needed in this field to develop a new methodology for efficient and inexpensive design to better protect buildings against progressive collapse.