Objective : This study was to examine a relationship among subjective psychological stress, physical stress response and oxidative stress. Methods : The subjects were consisted of 87 healthy volunteers. To assess subjective psychological stress, SRI(stress response inventory) was completed. To assess psychological and physical stress response, HRV(Heart Rate Variability) were tested. To assess oxidative stress, d-roms(Derivatives of reactive oxygen metabolites test) test was conducted. Subjects were divided into 3 groups depending on SRI(Stress Response Inventory) score, low stress response(LSR: lower than 30 percentile), Medium(MSR: 30-70 percentile) and high stress response(HSR: higher than 70 percentile). The Relationship between Stress Response and Oxidative Stress was estimated by correlation and One-way ANOVA analysis. Results : There were no significant differences of demographic data among 3 groups. There was a significant difference of oxidative stress among 3 groups. Conclusion : Our results suggest that there is a weak positive correlation between subjective psychological stress and oxidative stress. There is a significant difference of oxidative stress between HSR group and LSR group.