The purpose of this study was to investigate the biomechanical effects of an application of whole body vibration during strengthening exercise. Every participant performed four weeks exercise program using general leg-press versus vibrating leg-press. Participants did legpress exercise three sets of 25 repetitions with the load of 25 percent of 1RM during first week, three sets of 20 repetitions with 40 percent of 1RM during second week, three sets of 15 repetitions with 60 percents of 1RM during third week, and three sets of 15 repetitions with 80 percent of 1RM during last fourth week. The vibration(25Hz, 5mm) was applied only to the vibration exercise group. A three dimensional virtual lower extremity model for one of subject and virtual leg-press model were generated. The knee extensor muscle forces were analyzed using the virtual model and the knee joint torque(maximum extension torque) was measured using an isokinetic device. Calculated muscle forces were smaller in vibrating leg-press exercise than in general leg-press exercise. An increase of the maximum knee extension joint torque was 2.14 times larger approximately after the four week vibration leg-press exercise program was performed.