This study presents a new approach to pressure control of a impression cylinder for roll coater which is a kind of face pressure control between blanket roll and impression roll. Roll-to-Roll method for printing is a very useful tool for mass production such as RFID elements, smart sensors and solar cell devices. In this study, a decupling control strategy of the roll coater which is a combination of a cylinder system, a dry system and two pressure regulators with two pneumatic cylinders was discussed. Also, the characteristics of component such as a pressure regulator having a pressure reducing function and the movement of a blanket roll and a impression cylinder were analyzed using the Matlab software. From this results, the techniques of a shock and a vibration reduction were suggested.