In this paper, we proposed and analyzed the performance of the adaptive switching equalization for SC-FDMA system. It is well known that SC-FDMA system have a fairly similar structure to OFDMA system. Furthermore, SC-FDMA system has great advantage of low PAPR compare to OFDM system. However, this system often suffers from wireless channel characteristics such as multipath fading and increased channel impulse response and so on. To reduce this channel influence, it strongly requires efficient adaptive equalization. Therefore, the proposed system operated upon two modes namely, ZF mode for slow speed and MMSE mode for high speed. From the simulation results, we can confirm that the proposed scheme has more efficient performance from the system complexity point of view. So we can expect that the proposed system will be applied design of 3GPP LTE uplink.