The analog or partly digital typed interface of main control room in nuclear power plant (NPP) is gradually being replaced to the totally digitalized interface suitable for the digital environment. SKN 3,4 Nuclear Power Plant is currently developed in such a way to employ advanced displays and controls such as computerized procedure system(CPS), large display panel(LDP), and Soft control. According to the developed design process, the main control room (MCR) of the SKN3,4 was aesthetically designed based on a design concept of the health and sustainability and technically evaluated with human factors guidelines, which somehow lack of the confidence on the evaluation for the rapidly changing digital environment. The suitable review guideline for the digitalized interface and the environment was developed such as the guideline for CPS with information displays on VDU. For the guideline development, tremendous guidelines and technical papers related to evaluation issues of digital environment has been collected, analyzed and transformed to electric database forms and then built on database management system, called Design Review Supporting System to retrieve the appropriate issues for the practical usage of evaluators-in-field.