Purpose: The purpose of this study is to assess the effects of oriental medicine on secondary amenorrhea & hypomenorrhea objectively. Methods: By serum hormone assay and history interview, we classified the causes of each patient having secondary amenorrhea & hypomenorrhea. We also diagnosed and treated each patient according to them. And then we estimated the results of treatment by follow-up measurements of serum hormone level. Results: 1. We diagnosed case I as hypothalamic-pituitary disfunction, case II, III as PCOS and case IV as ovarian failure by classifying the causes from western medical scientific angle. 2. We also diagnosed and treated the cases from oriental medical scientific angle. 3. We confirmed the improvement of cases by follow-up measurements of serum hormone level. Conclusion: These results of serum hormone assay showed how medically effective oriental medical therapies of secondary amenorrhea & hypomenorrhea were.