Purpose: This study investigated trends in family nursing intervention studies and evaluated the quality of studies using the RCT design. Methods: This study included a total of 898 abstracts published from 1977 to 2007 in order to describe trends in family nursing intervention studies. Out of 898 studies, 153 RCT studies were selected for quality evaluation. The criteria of Jadad et al. (1996) were employed for the quality evaluation. Results: The number of RCT studies on family nursing interventions increased since 2001. Only 6.8% of the studies were published in the area of nursing. Most of the family interventions (27.1%) focused on individual family members and only 8.2% of the studies provided interventions to family as a whole unit. Nine different modes of family nursing intervention could be categorized, but none of the studies used the double blind design. Few studies utilized protocols for interventions. Only 17.5% of the studies reported the rationale for sample size. The mean score was 1.6 out of 5 according to the criteria of Jadad et al. (1996). Conclusion: Refined definitions and attributes of family nursing intervention modes are needed. Most of the studies did not meet the expectations of RCT. Thus, it is needed to improve the quality of design. More RCT studies should be conducted to provide evidence-based practice of family nursing interventions.