This study surveys the surface water environment in Southwest sea areas of Vietnam in order to evaluate the current environment. It collects and analyzes experimental results of programs, scientific subjects, and international projects relevant to ecological areas and coastlines of Kien Giang province. The methods analyzed and discussed by specialists are evaluated according to pollution coefficients established by the World Health Organization (WHO), sampling methods, and case study analyses. Comparison between the scale of pollution levels and the surface water quality in experimental areas of Long Xuyen Quadrangle shows a light-moderate pollution level. In Ca Mau Peninsula, the surface water source is only slightly polluted. Sea areas and islands are also light-moderately polluted. Computing results from water quality indices (WQI) show the level of pollution in experimental sites. Activities such as constructing infrastructures for tourism, exploiting minerals, and increasing population accelerate environmental pollution by deteriorating inherently sensitive ecosystems like corals, sea grass, mangrove swamps, and Melaleuca forests. Surveying and evaluating the present situation of surface water are fundamental solutions for environmental protection in the Southwest sea areas of Vietnam.