This article analyzes the evolutionary process of Daedeok Science Town from the standpoint of the life of science and technology poles. It deals the theoretical discussion on the science and technology poles, and investigates the history of Daedeok Science Town dividing into the period of conception, construction, and clustering. Daedeok Science Town has been developed from research and academic city through special research parks to innovative clusters, and nowadays emphasizes networking, interaction, and commercialization. This study shows the types of science and technology poles can be analyzed by historical consideration of specific Korean case.