Nowadays, manufacturing industry has been making its effort not only for productivity elevation but also for cost reduction in order to survive in the global market which is more and more challenging. In this paper, the method for planning of digital manufacturing system is proposed and door trim assembly system is determined as the subject of our research. First of all, the process sequence is generated based on the product analysis. And, the static and dynamic relationships between system components are represented using IDEF0 and UML model. The working time is estimated through the regression analysis based on MODAPTS method. According to the system configuration strategy, initial concept system layout is implemented 3D virtual environment. The problems caused by bad working motions are detected and modified through the ergonomic analysis using RULA method. According to proposed procedure, digital door trim assembly system is implemented in DLEMIA.