Penetration and installation of a new dynamic technology known as Flexible AC Transmission Systems (FACTS) in a practical and dynamic network requires and force expert engineer to develop robust and flexible strategy for planning and control. Unified Power Flow Controller (UPFC) is one of the recent and effective FACTS devices designed for multi control operation to enhance the power system security. This paper presents a dynamic strategy based on Particle Swarm Optimization (PSO) for optimal parameters setting of UPFC to enhance the system loadability. Firstly, we perform a multi power flow analysis with load incrementation to construct a global database to determine the initial efficient bounds associated to active power and reactive power target vector. Secondly a PSO technique applied to search the new parameters setting of the UPFC within the initial new active power and reactive power target bounds. The proposed approach is implemented with Matlab program and verified with IEEE 30-Bus test network. The results show that the proposed approach can converge to the near optimum solution with accuracy, and confirm that flexible multi-control of this device coordinated with efficient location enhance the system security of power system by eliminating the overloaded lines and the bus voltage violation.