In this paper, we propose a matrix based real-time pattern matching method, called MDPI, for real-time intrusion detection on several Gbps network traffic. Particularly, in order to minimize a kind of overhead caused by buffering, reordering, and reassembling under the circumstance where the incoming packet sequence is disrupted, MDPI adopts independent partial matching in the case dealing with pattern matching matrix. Consequently, we achieved the performance improvement of the amount of 61% and 50% with respect to TCAM method efficiency through several experiments where the average length of the Snort rule set was maintained as 9 bytes, and w=4 bytes and w=8bytes were assigned, respectively, Moreover, we observed the pattern scan speed of MDPI was 10.941Gbps and the consumption of hardware resource was 5.79LC/Char in the pattern classification of MDPI. This means that MDPI provides the optimal performance compared to hardware complexity. Therefore, by decreasing the hardware cost came from the increased TCAM memory efficiency, MDPI is proven the cost effective high performance intrusion detection technique.