An HTS power cable is generally composed of 2 layers for conducting and 1 layer for shielding. For the analysis of AC loss of an HTS power cable, 2-dimensional magnetic field analysis is carried out. The magnetization loss in HTS cable core was calculated, and the transport current loss was obtained from the monoblock equation and the elliptical Norris Equation. And the total AC loss of the cable was expected by the sum of magnetization loss and transport current loss. The variation of ac loss with respect to the gap and uncertain factor between the superconducting tapes was investigated, and the ac loss of 22.9kV/50MVA high-Tc superconducting power cable was calculated. These results well agree with those of experiment.