In this study, the anti oxidative effects, inhibitory effects on elastase, and components of Securinega suffruticosa extracts were investigated. The free radical (1,1-diphenyl-2-picrylhydrazyl, DPPH) scavenging activities ($FSC_{50}$) and reactive oxygen species ROS) scavenging activities ($OSC_{50}$) of extract/fractions from Securinega suffruticosa were measured. The aglycone fraction ($9.04;{pm};0.51;{mu}g/mL$) and 50 % ethanol extract ($1.05;{pm};0.41;{mu}g/mL$) showed the most effective scavenging activities. The protective effects on the rose-bengal sensitized photohemolysis of human erythrocytes were investigated. The aglycone fraction exhibited the most prominent cellular protective effect (${ au}_{50},;102.77;{pm};5.37$ min at $10{mu}g/mL$). The inhibitory effect of ethyl acetate fraction on tyrosinase were of examined ($210.0;{pm};1.02;{mu}g/mL$). The inhibitory effect of aglycone fraction on elastase were also investigated ($17.6;{pm};1.26;{mu}g/mL$). These results indicate that extract/fractions of Securinega suffruticosa can function as antioxidants in biological systems, particularly skin exposed to UV radiation by scavenging $^1O_2$ and other ROS, and protect cellular membranes against ROS. Securinega suffruticosa extract could be used as a new cosmeceutical ingredient for whitening and anti-wrinkle products.