Peroxisome proliferator-activated receptor $gamma$ (PPAR${gamma}$) is a ligand-activated transcription factor that is used as a target for anti-diabetic drug development. In a search for novel PPAR${gamma}$ agonists, the $eta$-carboxyethyl-rhodanine derivative SP1818 was identified. We report here the characteristics of SP1818 as a selective PPAR${gamma}$ agonist. In transactivation assays, SP1818 selectively activated PPAR${gamma}$, but the degree of PPAR${gamma}$ stimulation was less than with $1{mu}M$ rosiglitazone. SP1818 also stimulated glucose uptake in a concentration-dependent manner. The adipocyte differentiation markers adiponectin, scavenger receptor CD36 and aP2 were weakly induced by treatment with SP1818, and TRAP220 subunit was specifically recruited into PPAR${gamma}$ activated by rosiglitazone but not PPAR${gamma}$ activated by SP1818.