Stainless steel stamping multistage pump has become the mainstream of civil multi-stage pump. Combined with the technological features of stamping and welding pump, the studies of design for hydraulic parts of pump were come out. An $L_{18}$（$3^7$）orthogonal experiment was designed with seven factors and three values including blade inlet angle, impeller outer diameter, guide vane blade number, etc. 18 plans were designed. The two stage of whole flow field on stainless steel stamping multistage pump at design point for design was simulated by CFD. According to the test result and optimization design with experimental research, the trends of main parameters which affect hydraulic performance were got. After being manufactured and tested, the efficiency of the optimal model pump reaches 61.36% and the single head is more than 4.8 m. Compared with the standard efficiency of 53%, the design of the stainless steel stamping pump is successful. The result would be instructive to the design of Stainless steel stamping multistage pump designed by the impeller head maximum approach.